Description

5-Hydroxy-6α,7α-Epoxy-D(17A)-Homo-18-Nor-5α-Pregna-2,13,15,17-Tetrene-1,20-Dione is a high-purity, complex steroidal intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the field of endocrinology and hormone-related therapies. Its precise stereochemistry and functional groups make it an essential starting material for researchers and manufacturers developing next-generation steroid-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D labs for studying structure-activity relationships (SAR) and developing new therapeutic candidates.
• Hormone Analog Synthesis: Serves as a foundational structure for creating analogs with potential activity in hormonal pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialized steroid derivatives.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	5-Hydroxy-6α,7α-Epoxy-D(17A)-Homo-18-Nor-5α-Pregna-2,13,15,17-Tetrene-1,20-Dione
CAS No.	40071-61-2
Molecular Formula	C21H22O4
Molecular Weight	338.40 g/mol
Synonyms	5-Hydroxy-6α,7α-epoxy-17a-homo-18-nor-5α-pregna-2,13,15,17-tetraene-1,20-dione; 6α,7α-Epoxy-5-hydroxy-17a-homo-18-nor-5α-pregna-2,13,15,17-tetraene-1,20-dione; D(17A)-Homo-18-Nor-5α-pregna-2,13,15,17-tetraene-1,20-dione, 5-hydroxy-6α,7α-epoxy-; 40071-61-2; 5-Hydroxy-6,7-epoxy-D-homo-18-nor-5α-pregna-2,13,15,17-tetraene-1,20-dione
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-6α,7α-Epoxy-D(17A)-Homo-18-Nor-5α-Pregna-2,13,15,17-Tetrene-1,20-Dione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.