Description

5-Chloro-2,4-Dimethoxyphenyl Isothiocyanate is a versatile aromatic isothiocyanate derivative, a key building block in advanced organic synthesis. Its reactive isothiocyanate group makes it a critical intermediate for constructing heterocyclic compounds and functional molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and high-value materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides, leveraging its aromatic chloro and methoxy substituents.
• Ligand and Chelating Agent Precursor: The isothiocyanate group is utilized for the preparation of thiourea derivatives, which can act as ligands for metal complexes or catalysts.
• Material Science Research: Employed in the creation of functional polymers or advanced organic materials requiring specific aromatic and reactive handles.
• Chemical Biology Probe Development: Acts as a reactive handle for bioconjugation, labeling proteins, or other biomolecules for research applications.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and colorants where the chlorodimethoxyphenyl moiety imparts specific color or stability properties.

Basic Information

Product Name	5-Chloro-2,4-Dimethoxyphenyl Isothiocyanate
CAS No.	40046-27-3
Molecular Formula	C9H8ClNO2S
Molecular Weight	229.68 g/mol
Synonyms	5-Chloro-2,4-dimethoxyphenyl isothiocyanate; 2,4-Dimethoxy-5-chlorophenyl isothiocyanate; 1-Chloro-2,4-dimethoxy-5-isothiocyanatobenzene; Isothiocyanic acid, 5-chloro-2,4-dimethoxyphenyl ester; 5-Chloro-2,4-dimethoxybenzenisothiocyanate
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4-Dimethoxyphenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.