Description

1-C-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-1-S-Isobutyl-1-Thio-D-Xylitol is a high-purity nucleoside analog derivative, a key building block in advanced pharmaceutical research and development. This compound is valued for its role as a sophisticated intermediate in the synthesis of novel antiviral and anticancer agents, offering researchers precise molecular control. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Medicinal Chemistry Research: Serves as a key scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Used to create labeled or modified nucleosides for studying enzyme mechanisms and cellular pathways.
• Antiviral Agent Synthesis: A specialized building block for developing compounds targeting viral polymerases and replication mechanisms.
• Academic & Contract Research: Essential for universities and CROs conducting cutting-edge research in organic synthesis and bioorganic chemistry.
• Process Chemistry & Scale-Up: Supports the development of robust synthetic routes from laboratory to pilot-scale production for clinical candidates.

Basic Information

Product Name	1-C-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-1-S-Isobutyl-1-Thio-D-Xylitol
CAS No.	40031-69-4
Molecular Formula	C14H21N5O3S
Molecular Weight	339.41 g/mol
Synonyms	1-C-(6-Aminopurin-9-yl)-2,5-anhydro-1-S-isobutyl-1-thio-D-xylitol; 1-S-Isobutyl-1-thio-1-C-(6-aminopurin-9-yl)-2,5-anhydro-D-xylitol; 2,5-Anhydro-1-S-isobutyl-1-thio-1-C-(6-aminopurin-9-yl)-D-xylitol; Isobutylthioadenosine analog; Nucleoside analog intermediate; Purine xylitol derivative; Thionucleoside derivative
EINECS	Contact for details

Quality Control

Our production of 1-C-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-1-S-Isobutyl-1-Thio-D-Xylitol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and stored in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.