Description

Benzeneethanimidoyl Chloride, n-Hydroxy-α-Oxo- (9Ci) is a specialized organic building block of significant interest in advanced synthetic chemistry. This compound is valued for its unique bifunctional reactivity, serving as a key precursor for constructing complex heterocyclic and pharmaceutical intermediates. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing oxadiazole, isoxazole, or other nitrogen-oxygen heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive imidoyl chloride and oxo groups.
• Fine Chemical Production: Employed as a versatile building block for creating complex dyes, pigments, and functional organic materials.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Peptide Mimetic Chemistry: Facilitates the introduction of hydroxamic acid and related bioisosteric motifs into peptide backbones for drug discovery.

Basic Information

Product Name	Benzeneethanimidoyl Chloride, n-Hydroxy-α-Oxo- (9Ci)
CAS No.	4937-87-5
Molecular Formula	C8H6ClNO2
Molecular Weight	183.59 g/mol
Synonyms	N-Hydroxybenzeneethanimidoyl chloride, α-oxo-; 2-Chloro-N-hydroxy-2-phenylacetimidoyl chloride; Phenylglyoxylohydroxamic acid chloride; Benzoylformohydroxamic acid chloride; α-Oxo-N-hydroxybenzenecarboximidoyl chloride; (Chloro-hydroxyimino)phenylacetyl chloride; Hydroxamic acid chloride derivative of phenylglyoxylic acid
EINECS	Contact for details

Quality Control

Every batch of Benzeneethanimidoyl Chloride, n-Hydroxy-α-Oxo- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.