Description

2'-Deoxy-5-Iodouridine 3',5'-Dibenzoate is a chemically modified nucleoside derivative, specifically a protected form of 5-iodo-2'-deoxyuridine. This compound is a crucial synthetic intermediate in medicinal chemistry and oligonucleotide synthesis, valued for its role in introducing the iodouracil moiety into complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of antiviral agents, diagnostic probes, and novel therapeutic nucleosides.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used to incorporate modified bases into DNA/RNA strands for research and therapeutic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to thymidine metabolism.
• Diagnostic Probe Development: Utilized in creating labeled nucleotides for molecular imaging and detection assays.
• Radiopharmaceutical Precursor: Potential intermediate for compounds used in targeted radiotherapy.
• Academic & Industrial R&D: Fundamental material for exploring new chemical entities in drug discovery programs.

Basic Information

Product Name	2'-Deoxy-5-Iodouridine 3',5'-Dibenzoate
CAS No.	4833-07-2
Molecular Formula	C23H19IN2O7
Molecular Weight	562.31 g/mol
Synonyms	5-Iodo-2'-deoxyuridine 3',5'-dibenzoate; 5-Iododeoxyuridine Dibenzoate; IUdR Dibenzoate; 1-[(2R,4S,5R)-4-Benzoyloxy-5-(benzoyloxymethyl)tetrahydrofuran-2-yl]-5-iodopyrimidine-2,4-dione; 2'-Deoxy-5-iodouridine-3',5'-dibenzoate; 5-Iodo-1-(2-deoxy-3,5-di-O-benzoyl-β-D-erythro-pentofuranosyl)uracil
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-5-Iodouridine 3',5'-Dibenzoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. Handle and store under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.