Description

[3,4-Diacetyloxy-5-(6-Sulfanylidene-3H-Purin-9-Yl)Oxolan-2-Yl]Methyl A Cetate CAS NO 4754-05-6 is a chemically modified nucleoside derivative, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its value lies in its role as a versatile building block for the development of novel antiviral agents, nucleotide analogs, and other therapeutic compounds targeting specific enzymatic pathways. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers focused on oncology, virology, and metabolic disease research, where precise molecular modifications are required for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand purine metabolism and related pathways.
• Pro-drug Development: Serves as a modified nucleoside for creating pro-drugs with enhanced bioavailability and targeted delivery.
• Antiviral Agent Synthesis: Critical for the research and development of nucleotide analogs that act against DNA and RNA viruses.
• Labeled Compound Synthesis: Used as a starting material for incorporating isotopic labels (e.g., deuterium, carbon-13) for tracer studies.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses requiring protected or functionalized nucleoside scaffolds.

Basic Information

Product Name	[3,4-Diacetyloxy-5-(6-Sulfanylidene-3H-Purin-9-Yl)Oxolan-2-Yl]Methyl A Cetate
CAS No.	4754-05-6
Molecular Formula	C16H18N4O8S
Molecular Weight	426.40 g/mol
Synonyms	9-[(2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)oxolan-2-yl]-6-sulfanylidene-3H-purin-2-one; 6-Thioxo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine; 2',3',5'-Tri-O-acetyl-6-thioguanosine; 6-Thioguanosine 2',3',5'-triacetate; 6-Thioguanosine triacetate; 6-TGTPA; 6-Thio-GTPA; 6-Thioguanine riboside triacetate
EINECS	Contact for details

Quality Control

Our production of [3,4-Diacetyloxy-5-(6-Sulfanylidene-3H-Purin-9-Yl)Oxolan-2-Yl]Methyl A Cetate adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.