Description

(22E,24S)-22,23-Didehydro-24-Ethyl-5α-Cholestan-3β-Ol is a high-purity, semi-synthetic sterol derivative with a defined stereochemical configuration. This compound serves as a critical advanced intermediate and reference standard in the research and development of novel pharmaceutical agents and bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry, metabolic pathway studies, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based therapeutics and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies of cholesterol metabolism, membrane biophysics, and sterol-protein interactions.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex steroidal compounds with potential biological activity.
• Analytical Standard: Employed in analytical methods such as HPLC and GC for the identification and quantification of sterols in complex matrices.
• Nutraceutical R&D: Investigated for potential applications in the development of specialized dietary supplements and functional ingredients.

Basic Information

Product Name	(22E,24S)-22,23-Didehydro-24-Ethyl-5α-Cholestan-3β-Ol
CAS No.	4736-96-3
Molecular Formula	C₂₉H₄₈O
Molecular Weight	412.70 g/mol
Synonyms	24-Ethylcholesta-5,22-dien-3β-ol; 24-Ethyl-5α-cholesta-5,22-dien-3β-ol; Stigmasta-5,22-dien-3β-ol; (22E)-Stigmasta-5,22-dien-3β-ol; 5α-Stigmasta-5,22-dien-3β-ol; 24-Ethylcholest-5,22-dien-3β-ol; δ²²-Stigmastenol
EINECS	Contact for details

Quality Control

Our (22E,24S)-22,23-Didehydro-24-Ethyl-5α-Cholestan-3β-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets the exacting standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Specified range available on COA
Specific Rotation	Specified range available on COA
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.