Description

3-β-D-Ribofuranosyl-3H-1,2,3-Triazolo[4,5-D]Pyrimidine-5,7(4H,6H)-Dione is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway investigations.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Nucleoside Analog Development: Fundamental for creating modified nucleosides with potential therapeutic activity against viruses and tumors.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry and bioorganic mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Product Name	3-β-D-Ribofuranosyl-3H-1,2,3-Triazolo[4,5-D]Pyrimidine-5,7(4H,6H)-Dione
CAS No.	4730-45-4
Molecular Formula	C9H11N5O6
Molecular Weight	285.22 g/mol
Synonyms	8-Azaadenosine; 8-Aza-adenosine; 8-Azadenosine; 3-β-D-Ribofuranosyl-3H-v-triazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione; 3H-1,2,3-Triazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione, 3-β-D-ribofuranosyl-; 8-Aza-Adenosine; NSC 51046
EINECS	Contact for details

Quality Control

Our 3-β-D-Ribofuranosyl-3H-1,2,3-Triazolo[4,5-D]Pyrimidine-5,7(4H,6H)-Dione is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.