Description

Fosfomycin Sodium is a broad-spectrum antibiotic belonging to the phosphonic acid class, widely recognized for its unique mechanism of action that inhibits bacterial cell wall synthesis. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy against a range of Gram-positive and Gram-negative bacteria, including multi-drug resistant strains. It is essential for manufacturers in the pharmaceutical industry developing injectable and oral antibiotic formulations for human and veterinary medicine.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable and oral antibiotic medications for systemic infections.
• Urinary Tract Infection (UTI) Treatment: Key component in formulations specifically targeting uncomplicated UTIs.
• Veterinary Pharmaceuticals: Used in antibiotic preparations for treating bacterial infections in livestock and companion animals.
• Combination Therapy: Employed in synergistic antibiotic combinations to combat resistant bacterial pathogens.
• Research & Development: Serves as a reference standard and building block in microbiological and pharmacological research.
• Hospital Formulary: Critical for compounding pharmacies and hospital settings for preparing specific dosage forms.

Basic Information

Product Name	Fosfomycin Sodium
CAS No.	4719-75-9
Molecular Formula	C3H5Na2O4P
Molecular Weight	182.02 g/mol
Synonyms	Fosfomycin Disodium Salt; Phosphomycin Disodium; (3-Methyloxiran-2-yl)phosphonic Acid Disodium Salt; Fosfomycin Disodium; Antibiotic MK-955; Fosfomycin Sodium Salt; Fosfomycin Na2; Monurol (brand name reference); FR-31564
EINECS	225-231-5

Quality Control

Our Fosfomycin Sodium is manufactured under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical applications, with typical grades conforming to in-house specifications aligned with major pharmacopoeial guidelines. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure traceability and consistency to support our clients' regulatory and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (10% solution)	8.0 - 10.0
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Bacterial Endotoxins	< 0.17 EU/mg (for injectable grade)
Microbial Enumeration	Conforms to EP/USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.