Description

16-o-Deacetylfusidic Acid Lactone is a key chemical intermediate and derivative of fusidic acid, a potent antibiotic. This compound is of significant interest in pharmaceutical research and development due to its role in the synthesis and structural modification of novel antimicrobial agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new antibiotics and the study of bacterial resistance mechanisms.

Application

• Pharmaceutical Intermediate: A critical building block in the semi-synthesis of novel fusidic acid derivatives and other steroidal antibiotics.
• Antimicrobial Research: Used as a reference standard and active material in microbiological assays to study structure-activity relationships (SAR).
• Biochemical Studies: Employed in research to investigate the mechanism of action of fusidic acid and its analogs on bacterial protein synthesis.
• API Development: Serves as a precursor in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) targeting Gram-positive bacteria.
• Quality Control: Acts as a high-purity impurity standard for the analytical testing and validation of fusidic acid and related pharmaceutical products.

Basic Information

Product Name	16-o-Deacetylfusidic Acid Lactone
CAS No.	4701-54-6
Molecular Formula	C31H46O6
Molecular Weight	514.70 g/mol
Synonyms	16-Deacetylfusidic Acid Lactone; 16-Deacetylfusidic Acid δ-Lactone; (3β,4α,8α,9β,11α,13α,14β,16β,17Z)-13,27-Epoxy-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethyl-1,2,3,4,4a,5,6,8,9,10,11,12,13,14,14a,15,16,16a-octadecahydro-17H-cyclopenta[a]phenanthrene-1,17-dione; Fusidic Acid Lactone Derivative
EINECS	Contact for details

Quality Control

Our 16-o-Deacetylfusidic Acid Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.