Description

19-Nordeoxycorticosterone is a synthetic steroid derivative of deoxycorticosterone, a key mineralocorticoid hormone precursor. This compound is of significant interest in pharmaceutical research and development for its role in studying steroid hormone biosynthesis, metabolism, and receptor interactions. It serves as a critical intermediate and reference standard for laboratories and manufacturers in the pharmaceutical, biotechnology, and life science research sectors, enabling the development of novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Used in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Biochemical Research: Serves as a reference standard and analytical tool in studies of adrenal steroidogenesis, enzyme inhibition, and metabolic pathways.
• Endocrinology Studies: Employed in laboratory research to investigate mineralocorticoid and glucocorticoid receptor activity and signaling mechanisms.
• Quality Control & Analytical Testing: Used as a certified reference material (CRM) in HPLC, GC-MS, and other analytical methods for method validation and quality assurance in pharmaceutical manufacturing.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting fundamental studies in steroid chemistry and hormone biology.

Basic Information

Product Name	19-Nordeoxycorticosterone
CAS No.	4682-70-6
Molecular Formula	C₂₁H₃₀O₃
Molecular Weight	330.46 g/mol
Synonyms	19-Nor-DOC; 19-Nor-Deoxycorticosterone; 19-Nor-11-Deoxycorticosterone; 21-Hydroxy-19-norpregn-4-ene-3,20-dione; 19-Nor-21-hydroxy-4-pregnene-3,20-dione; 19-Nor-11-deoxycorticosterone; 19-Nor-DOC Acetate (related ester)
EINECS	Contact for details

Quality Control

Our 19-Nordeoxycorticosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.