Description

3Alpha-Hydroxy-7-Oxo-5Beta-Cholanic Acid is a key bile acid derivative and an important intermediate in steroid chemistry. This compound is valued for its role as a versatile synthetic precursor in the production of more complex pharmaceutical agents and biochemical research tools. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for developing therapeutic compounds and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of ursodeoxycholic acid (UDCA) analogs and other therapeutic bile acids.
• Biochemical Research: Used as a standard or reagent in studies of bile acid metabolism, liver function, and cholesterol homeostasis.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical manufacturing and regulatory testing.
• Fine Chemical Synthesis: Employed in organic synthesis to introduce the steroidal core structure into more complex molecules for drug discovery.
• Metabolic Pathway Studies: Utilized in research to investigate enzymatic pathways involving bile acid synthesis and modification.

Basic Information

Product Name	3Alpha-Hydroxy-7-Oxo-5Beta-Cholanic Acid
CAS No.	4651-67-6
Molecular Formula	C₂₄H₃₈O₄
Molecular Weight	390.56 g/mol
Synonyms	7-Ketolithocholic Acid; 3α-Hydroxy-7-oxo-5β-cholan-24-oic Acid; 7-Oxolithocholic Acid; 3α-Hydroxy-7-oxolithocholic Acid; 7-Keto-3α-hydroxycholanic Acid; 5β-Cholan-24-oic acid, 3α-hydroxy-7-oxo-; 7-Ketolithocholate
EINECS	225-074-4

Quality Control

Our 3Alpha-Hydroxy-7-Oxo-5Beta-Cholanic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical intermediates and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.