Description

3β,12β,14β-Trihydroxypregn-5-En-20-One CAS NO 4644-99-9 is a high-purity steroid derivative, specifically a trihydroxylated pregnenolone analog. This compound serves as a critical intermediate in the synthesis of complex steroid-based pharmaceuticals and fine chemicals, where precise stereochemistry is paramount. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of specialized corticosteroids and other bioactive steroid molecules.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme inhibition assays.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and steroidal compounds for material science.
• API Development: Serves as a starting material or intermediate in the research and development of new Active Pharmaceutical Ingredients (APIs).
• Laboratory Reagent: Utilized in analytical and research laboratories for method development and calibration.

Basic Information

Product Name	3β,12β,14β-Trihydroxypregn-5-En-20-One
CAS No.	4644-99-9
Molecular Formula	C₂₁H₃₂O₄
Molecular Weight	348.48 g/mol
Synonyms	3β,12β,14β-Trihydroxypregn-5-en-20-one; (3β,12β,14β)-Pregn-5-ene-3,12,14-triol-20-one; 3β,12β,14β-Trihydroxy-5-pregnen-20-one; Pregn-5-ene-3β,12β,14β-triol-20-one; 4644-99-9
EINECS	Contact for details

Quality Control

Our 3β,12β,14β-Trihydroxypregn-5-En-20-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediates and research chemicals. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.