Description

4-Chlorobutyryl Chloride is a versatile and highly reactive organic acid chloride intermediate. This compound is essential for introducing the 4-chlorobutyryl moiety into target molecules, enabling the synthesis of complex chemical structures. It is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various active pharmaceutical ingredients (APIs), including potential GABA receptor modulators and other neuroactive compounds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the chlorobutyryl functional group.
• Polymer Chemistry: Serves as a monomer or modifying agent in the production of specialty polymers and resins with tailored properties.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other reactions to introduce acyl groups into aromatic and heterocyclic systems.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Research & Development: A valuable tool in medicinal chemistry and material science R&D for creating novel molecular entities.

Basic Information

Product Name	4-Chlorobutyryl Chloride
CAS No.	4635-59-0
Molecular Formula	C4H6Cl2O
Molecular Weight	141.00 g/mol
Synonyms	γ-Chlorobutyryl Chloride; 4-Chlorobutanoyl Chloride; Butanoyl chloride, 4-chloro-; NSC 9375; 1-Chloro-4-chlorocarbonylbutane; 4-Chloro-1-oxobutyl chloride
EINECS	225-052-3

Quality Control

Our 4-Chlorobutyryl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards where applicable, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and incompatible materials. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.