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3β-[(6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-7β,8-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide CAS NO 4589-95-1


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CAS No.:4589-95-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-7β,8-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a compound class known for its potent biological activity. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular functions. It serves as a key building block for medicinal chemists and advanced manufacturers in the pharmaceutical and biotechnology sectors requiring precise, high-quality raw materials.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel cardiac glycoside-based drugs and therapeutic candidates.
  • Biochemical Research: Used as a reference standard or active compound in studies investigating ion channel modulation (Na+/K+-ATPase) and cardiac cell physiology.
  • Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies to develop new molecules with optimized potency and safety profiles.
  • API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients (APIs) with cardioprotective or inotropic potential.
  • Academic Research: Utilized in university and institutional labs for pharmacological and toxicological investigations of cardenolide compounds.

Basic Information

Product Name 3β-[(6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-7β,8-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No. 4589-95-1
Molecular Formula C30H44O9
Molecular Weight 548.67 g/mol
Synonyms Digitoxigenin 3-O-α-L-oleandroside; Oleandrigenin 3-O-α-L-oleandroside; 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-7β,8-epoxy-14-hydroxy-5β-card-20(22)-enolide; 3-O-α-L-Oleandrosyl-digitoxigenin; 16-Formylgitoxigenin 3-O-α-L-oleandroside; Anhydro-oleandrin genin 3-O-oleandroside; 3-Epi-16-formylgitoxigenin 3-O-α-L-oleandroside
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Quality Control

Our 3β-[(6-Deoxy-3-o-Methyl-α-L-Glucopyranosyl)Oxy]-7β,8-Epoxy-14-Hydroxy-5β-Card-20(22)-Enolide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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