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2'-Deoxynebularine CAS NO 4546-68-3


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CAS No.:4546-68-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2'-Deoxynebularine is a purine nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and reference standard in the study of nucleoside metabolism, enzyme inhibition, and antiviral drug development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleotide synthesis and medicinal chemistry.

Application

  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for adenosine deaminase and other nucleoside-processing enzymes.
  • Pharmaceutical R&D: Serves as a key intermediate or precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
  • Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS applications.
  • Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to explore new therapeutic agents.
  • Academic Research: Utilized in universities and research institutes for fundamental studies on nucleic acid chemistry and cellular metabolism.

Basic Information

Product Name 2'-Deoxynebularine
CAS No. 4546-68-3
Molecular Formula C10H12N4O3
Molecular Weight 236.23 g/mol
Synonyms 9-(2-Deoxy-β-D-erythro-pentofuranosyl)purine; 2'-Deoxynebularine; 9-(2-Deoxy-β-D-ribofuranosyl)purine; 2'-Deoxypurine riboside; Deoxynebularine; Purine, 9-(2-deoxy-β-D-erythro-pentofuranosyl)-; 2'-Deoxy-purine ribonucleoside
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Quality Control

Our 2'-Deoxynebularine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality parameters include identity confirmation by spectroscopic methods and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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