Description

3-Oxo-5β-Carda-8(14),20(22)-Dienolide CAS NO 4521-89-5 is a high-purity steroidal cardenolide derivative, a key advanced intermediate in the synthesis of specialized pharmaceutical compounds. Its value lies in its defined molecular structure, which serves as a critical building block for developing novel therapeutic agents with targeted biological activity. This compound is essential for research institutions and pharmaceutical manufacturers focused on cardiovascular drug discovery, steroid chemistry, and the development of new bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex cardiotonic steroids and other bioactive steroidal molecules.
• Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) within the cardenolide class of compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Employed as a specialized building block in organic synthesis for introducing the cardenolide skeleton into more complex molecular architectures.
• Biochemical Research: Utilized in studies investigating the interaction of cardenolides with biological targets such as the Na+/K+-ATPase enzyme.

Basic Information

Product Name	3-Oxo-5β-Carda-8(14),20(22)-Dienolide
CAS No.	4521-89-5
Molecular Formula	C23H30O4
Molecular Weight	370.48 g/mol
Synonyms	3-Oxo-5β-carda-8(14),20(22)-dienolide; 5β-Carda-8(14),20(22)-dienolide-3-one; 3-Keto-5β-carda-8(14),20(22)-dienolide; 3-Oxo-5β,14β-carda-8(14),20(22)-dienolide; 8(14),20(22)-Cardenolide Dien-3-one; 5β,14β-Carda-8(14),20(22)-dienolide-3-one; Carda-8(14),20(22)-dienolide-3-one; 4521-89-5 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Oxo-5β-Carda-8(14),20(22)-Dienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.