Description

3,4,5-Trimethoxybenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 3,4,5-trimethoxybenzoyl moiety into target molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for neurological and cardiovascular therapies.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the trimethoxyphenyl group is a key pharmacophore.
• Fine Chemical Building Block: Essential for constructing complex molecules in research and development for dyes, pigments, and specialty polymers.
• Peptide Coupling Reagent: Acts as a coupling agent or protecting group activator in peptide synthesis and related biochemical applications.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Material Science Research: Used to modify surfaces or create novel monomers for advanced polymeric materials with specific properties.

Basic Information

Product Name	3,4,5-Trimethoxybenzoyl Chloride
CAS No.	4521-61-3
Molecular Formula	C10H11ClO4
Molecular Weight	230.64 g/mol
Synonyms	3,4,5-Trimethoxybenzoyl chloride; Galloyl chloride, 3,4,5-trimethoxy-; 3,4,5-Trimethoxybenzoic acid chloride; Trimethoxybenzoyl chloride; 4521-61-3; EINECS 224-857-4; NSC 406912; Benzoic acid, 3,4,5-trimethoxy-, chloride
EINECS	224-857-4

Quality Control

Our 3,4,5-Trimethoxybenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.