Description

5-Formyl-2'-Deoxyuridine is a modified nucleoside derivative of deoxyuridine, featuring a formyl group at the 5-position of the uracil base. This specific functionalization makes it a valuable intermediate and building block in the synthesis of more complex nucleoside analogs and oligonucleotides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and diagnostic probes. The compound is supplied with a high level of purity to ensure reliable and reproducible results in sensitive biochemical applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Oligonucleotide Synthesis: Serves as a modified monomer for incorporating specific functionalities into DNA strands for research and diagnostic purposes.
• Prodrug Development: Utilized in the design and synthesis of prodrugs to enhance the delivery and efficacy of therapeutic agents.
• Reference Standard: Employed as an analytical standard in quality control and method development for pharmaceutical analysis.
• Life Science Reagents: Component in the formulation of specialized reagents for molecular biology and genetic research.

Basic Information

Item	Detail
Product Name	5-Formyl-2'-Deoxyuridine
CAS No.	4494-26-2
Molecular Formula	C10H12N2O6
Molecular Weight	256.21 g/mol
Synonyms	5-Formyldeoxyuridine; 5-FordU; 5-Carbaldehyde-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-formylpyrimidine-2,4-dione; 2'-Deoxy-5-formyluridine; 5-Formyl-dUrd; 5-FO-dU
EINECS	Contact for details

Quality Control

Our 5-Formyl-2'-Deoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets high-grade specifications suitable for research and pharmaceutical development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.