Description

3β,5-Dihydroxy-19-Oxocarda-14,20(22)-Dienolide is a high-purity, specialized cardenolide derivative with significant potential in pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of novel cardiac glycosides and other bioactive steroidal molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and other steroidal drugs targeting heart conditions.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cellular mechanisms.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized efficacy and safety profiles.
• Analytical Standard: Employed as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses for quality control and method development.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies of cardenolide compounds.

Basic Information

Product Name	3β,5-Dihydroxy-19-Oxocarda-14,20(22)-Dienolide
CAS No.	4480-65-3
Molecular Formula	C₂₃H₃₂O₅
Molecular Weight	388.50 g/mol
Synonyms	19-Oxocarda-14,20(22)-dienolide-3β,5-diol; 3β,5-Dihydroxy-19-oxocarda-14,20(22)-dienolide; 19-Oxo-3β,5-dihydroxycarda-14,20(22)-dienolide; 3β,5,19-Trihydroxycarda-14,20(22)-dienolide 19→5 lactone; Card-20(22)-enolide-3β,5-diol-19-one; 19-Oxodigitoxigenin derivative
EINECS	Contact for details

Quality Control

Every batch of 3β,5-Dihydroxy-19-Oxocarda-14,20(22)-Dienolide is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to support your research and regulatory needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment ensures the material is suitable for use as a pharmaceutical reference standard and advanced intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.