Description

4-(Chlorocarbonyl)Phenyl Sulfone is a high-purity, reactive chemical intermediate characterized by its sulfone and acid chloride functional groups. This compound is critical for introducing the 4-(sulfonyl)benzoyl moiety into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought by manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfone-containing active pharmaceutical ingredients (APIs), including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the sulfone group enhances biological activity and stability.
• Polymer Modification: Serves as a monomer or cross-linking agent for engineering high-performance polymers, such as poly(arylene ether sulfone)s, with enhanced thermal and chemical resistance.
• Liquid Crystal & OLED Materials: A precursor for creating charge-transport or emissive materials in electronic displays and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments that require sulfone groups for color fastness and solubility properties.
• Cross-coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create biaryl systems.

Basic Information

Product Name	4-(Chlorocarbonyl)Phenyl Sulfone
CAS No.	4462-61-7
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	4-(Chlorosulfonyl)benzoic acid chloride; 4-Carboxybenzenesulfonyl chloride; p-Sulfobenzoic acid chloride; Benzoic acid, 4-(chlorosulfonyl)-, chloride; 4-(Chlorosulfonyl)benzoyl chloride; p-(Chlorocarbonyl)benzenesulfonyl chloride; 4-Sulfobenzoic acid dichloride
EINECS	224-713-6

Quality Control

Our 4-(Chlorocarbonyl)Phenyl Sulfone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Water Content (KF)	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.