Description

2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl Chloride is a key glycosyl donor and protected sugar intermediate in organic synthesis. This compound is essential for the efficient construction of complex carbohydrate structures and glycoconjugates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science industries for the development of novel therapeutics, bioactive molecules, and advanced materials.

Application

• Glycosylation Reactions: A crucial building block for the stereoselective synthesis of O-glycosidic bonds in oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and antibiotic drugs.
• Carbohydrate Chemistry Research: Serves as a fundamental reagent in academic and industrial laboratories for studying glycosylation mechanisms and developing new synthetic methodologies.
• Glycoprotein & Glycolipid Synthesis: Integral to the semi-synthesis and modification of biologically important glycoproteins and glycolipids for biochemical studies.
• Agrochemical Development: Employed as an intermediate in the synthesis of certain herbicides, fungicides, and plant growth regulators with carbohydrate motifs.
• Diagnostic Reagent Production: Used in the manufacture of specialized reagents and probes for glycan analysis and detection in diagnostic kits.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl Chloride
CAS No.	4451-36-9
Molecular Formula	C14H19ClO9
Molecular Weight	366.75 g/mol
Synonyms	Acetobromoglucose (common misnomer for chloride analog); 2,3,4,6-Tetra-O-acetyl-α/β-D-glucopyranosyl Chloride (mixed anomers); 1-Chloro-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose; Tetraacetylglucosyl Chloride; β-D-Glucopyranosyl Chloride, 2,3,4,6-Tetraacetate; Glucosyl Chloride Tetraacetate; Acetylated Glucosyl Chloride
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC/NMR), anomeric ratio, moisture content, and residual solvents. Our quality system is designed to support cGMP and ISO standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
β-Anomer Content (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.