Description

2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Chloride is a key glycosyl donor and protected sugar intermediate in organic synthesis. This compound is critical for the efficient and stereoselective construction of complex carbohydrate structures and glycoconjugates. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel therapeutics, diagnostics, and bioactive molecules.

Application

• Glycosylation Reactions: As a versatile glycosyl donor for the synthesis of oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediates: In the research and production of active pharmaceutical ingredients (APIs) for antiviral, anticancer, and antibiotic drugs.
• Carbohydrate Chemistry Research: A fundamental building block for academic and industrial research into carbohydrate-based chemistry and biology.
• Glycoconjugate Synthesis: For creating labeled sugars, probes, and conjugates used in biochemical assays and diagnostic tools.
• Fine Chemical Synthesis: As a chiral precursor or intermediate in the synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Chloride
CAS No.	4451-35-8
Molecular Formula	C14H19ClO9
Molecular Weight	366.75 g/mol
Synonyms	Acetobromo-α-D-glucose (common misnomer for chloride analog); 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl chloride; α-D-Glucopyranosyl chloride, 2,3,4,6-tetraacetate; Tetraacetyl-α-D-glucosyl chloride; 1-Chloro-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose; Acetylated glucosyl chloride; α-Acetochloroglucose
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.