Description

(5Beta)-12,Beta,14-Dihydroxy-3-Oxocard-20(22)-Enolide is a high-purity, specialized cardenolide derivative, a class of compounds known for their potent biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard in research and development. It is primarily required by pharmaceutical manufacturers and biochemical research institutions for the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of cardenolides and their interaction with biological targets like Na+/K+-ATPase.
• Preclinical Studies: Serves as a starting material or an active compound analog in pharmacological and toxicological research.
• Academic Research: Utilized in universities and research institutes for organic synthesis projects and medicinal chemistry programs.

Basic Information

Product Name	(5Beta)-12,Beta,14-Dihydroxy-3-Oxocard-20(22)-Enolide
CAS No.	4442-17-5
Molecular Formula	C23H32O6
Molecular Weight	404.50 g/mol
Synonyms	12β,14-Dihydroxy-3-oxocard-20(22)-enolide; 3-Oxo-12β,14-dihydroxycard-20(22)-enolide; 12β,14-Dihydroxy-3-oxo-5β-card-20(22)-enolide; 5β-Card-20(22)-enolide-3,12,14-trione, 14-hydroxy-; 12β,14-Dihydroxy-3-oxo-5β,14β-card-20(22)-enolide; Cardenolide derivative 4442-17-5
EINECS	Contact for details

Quality Control

Our (5Beta)-12,Beta,14-Dihydroxy-3-Oxocard-20(22)-Enolide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.