Description

Isothiocyanatophenyl Sulfone is a versatile and reactive chemical intermediate characterized by the presence of both an isothiocyanate group and a sulfone moiety. This bifunctional nature makes it a valuable building block for the synthesis of more complex molecules, particularly in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting specific enzymes or receptors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Polymer Modification: Acts as a cross-linking agent or functional monomer to introduce sulfone and thiourea linkages into polymers, enhancing thermal stability and mechanical properties.
• Bioconjugation Chemistry: The isothiocyanate group is reactive towards amines, making this compound useful for labeling proteins, antibodies, or other biomolecules in diagnostic and research applications.
• Material Science Research: Employed in the creation of advanced organic frameworks, coatings, or adhesives with specific performance characteristics.
• Chemical Synthesis Reagent: A versatile reagent for constructing heterocyclic compounds and other complex organic structures in academic and industrial laboratories.

Basic Information

Product Name	Isothiocyanatophenyl Sulfone
CAS No.	4430-49-3
Molecular Formula	C7H5NO2S2
Molecular Weight	199.25 g/mol
Synonyms	4-Isothiocyanatophenyl sulfone; 1-Isothiocyanato-4-(phenylsulfonyl)benzene; p-Isothiocyanatophenyl sulfone; Benzenesulfonyl phenyl isothiocyanate; (4-Isothiocyanatophenyl)(phenyl)methanone (incorrect but common misnomer); 4-(Phenylsulfonyl)phenyl isothiocyanate; NSC 403119
EINECS	Contact for details

Quality Control

Our Isothiocyanatophenyl Sulfone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.