Description

5ξ-Cardanolide is a high-purity, specialized steroidal lactone compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique structural framework makes it a valuable intermediate for the development of novel bioactive molecules and complex natural product analogs. This compound is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of steroidal drugs and potential therapeutic agents targeting hormone receptors.
• Natural Product Synthesis: Used as a core scaffold for the total synthesis or semi-synthesis of complex cardenolide and bufadienolide natural products.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new compounds with targeted biological activity.
• Reference Standard: Acts as an analytical standard for quality control and identification in laboratories studying cardenolide-class compounds.
• Biochemical Research: Utilized in studies investigating the interaction of cardenolides with biological systems, such as Na+/K+-ATPase inhibition.
• Fine Chemical Production: Functions as a specialized intermediate for creating high-value, complex molecules for various industrial research applications.

Basic Information

Product Name	5ξ-Cardanolide
CAS No.	4427-84-3
Molecular Formula	C23H34O4
Molecular Weight	374.52 g/mol
Synonyms	5ξ-Cardanolide; 5xi-Cardanolide; Card-20(22)-enolide, 3,14-dihydroxy-, (3β,5ξ)-; (3β,5ξ)-3,14-Dihydroxycard-20(22)-enolide; 3β,5ξ,14β-Cardanolide; 5-Epicardanolide; NSC 10447; 5-ξ-Cardanolide
EINECS	Contact for details

Quality Control

Our 5ξ-Cardanolide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a well-ventilated area and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.