Description

3β,12β-Dihydroxy-5β-Carda-14,20(22)-Dienolide is a high-purity cardenolide derivative, a class of compounds known for their potent biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for research and quality control. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the development and production of specialized therapeutics and analytical methods.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and other specialized active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity calibration standard in analytical laboratories for HPLC, LC-MS, and NMR to ensure product quality and regulatory compliance.
• Biochemical Research: Employed in pharmacological and biological studies to investigate structure-activity relationships (SAR) and mechanisms of action related to Na+/K+-ATPase inhibition.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for the custom synthesis of complex organic molecules and derivatives for specialized applications.

Basic Information

Product Name	3β,12β-Dihydroxy-5β-Carda-14,20(22)-Dienolide
CAS No.	4427-80-9
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	3β,12β-Dihydroxy-5β-card-14,20(22)-dienolide; 3β,12β-Dihydroxy-5β-carda-14,20(22)-dienolide; 14,20(22)-Dienolide-3β,12β-diol; (3β,5β,12β)-3,12-Dihydroxy-14,20(22)-cardenolide; Cardenolide derivative 4427-80-9; 5β-Carda-14,20(22)-dienolide-3β,12β-diol
EINECS	Contact for details

Quality Control

Our 3β,12β-Dihydroxy-5β-Carda-14,20(22)-Dienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.