Description

3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-16β-(Acetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide is a highly specialized cardiac glycoside derivative, a class of compounds known for their potent biological activity. This compound is of significant interest in pharmaceutical research and development, particularly for its structural complexity and potential as a key intermediate or reference standard. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis and study of novel therapeutic agents targeting cardiovascular functions.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of novel cardiac glycoside analogs for therapeutic exploration.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and compound identification via HPLC, LC-MS, or NMR.
• Biochemical Studies: Employed in pharmacological and biochemical research to investigate mechanisms of action related to sodium-potassium ATPase inhibition and cardiac contractility.
• Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry, natural product synthesis, and structure-activity relationship (SAR) analysis.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and process optimization for the production of related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-16β-(Acetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No.	4420-66-0
Molecular Formula	C34H48O12
Molecular Weight	648.74 g/mol
Synonyms	16β-Acetoxy-3β-[(2-O-acetyl-6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; 3β-[(2-O-Acetyl-6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-16β-(acetyloxy)-14-hydroxy-5β-card-20(22)-enolide; 16β-Acetylgitoxin; Gitoxin 16-acetate; 3'-O-Acetyl-6'-deoxy-3'-O-methyloleandrin; A derivative of Gitoxin; Cardiac glycoside derivative
EINECS	Contact for details

Quality Control

Our 3β-[(2-o-Acetyl-6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-16β-(Acetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing desiccated at -20°C. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.