Description

1-Adamantyl Isothiocyanate is a high-value, functionalized adamantane derivative characterized by its robust, cage-like molecular structure and reactive isothiocyanate group. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the creation of novel materials and bioactive molecules with enhanced stability and performance. It is primarily needed by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and material science sectors for developing new drug candidates, ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies, leveraging the adamantane moiety's lipophilicity and metabolic stability.
• Agrochemical Research: Used in developing new crop protection agents and pesticides, where the adamantyl group can impart resistance to degradation and improve bioavailability.
• Material Science: Acts as a monomer or cross-linking agent in the production of high-performance polymers, resins, and coatings with superior thermal and chemical resistance.
• Chemical Biology & Proteomics: Utilized as an affinity probe or labeling reagent due to the reactive isothiocyanate group, which readily forms thiourea bonds with amines in proteins and peptides.
• Ligand Synthesis for Catalysis: Employed to create sophisticated ligands for transition metal catalysts, enhancing selectivity and efficiency in asymmetric synthesis and other catalytic processes.
• Advanced Organic Synthesis: A valuable scaffold for constructing complex, three-dimensional molecular architectures in medicinal and process chemistry.

Basic Information

Product Name	1-Adamantyl Isothiocyanate
CAS No.	4411-26-1
Molecular Formula	C11H15NS
Molecular Weight	193.31 g/mol
Synonyms	Adamantan-1-yl isothiocyanate; 1-Isothiocyanatoadamantane; 1-Adamantylisothiocyanate; NSC 163063; Adamantane-1-isothiocyanate; Tricyclo[3.3.1.13,7]decan-1-yl isothiocyanate
EINECS	Contact for details

Quality Control

Our 1-Adamantyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.