Description

Alanine, 3-[4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl]-, Monosodium Salt (8Ci) is a specialized iodinated aromatic amino acid derivative, serving as a critical synthetic intermediate and research chemical. Its unique structure, featuring multiple iodine atoms, makes it a valuable building block for the development of novel compounds in pharmaceutical and diagnostic research. This high-purity material is essential for researchers and manufacturers in the life sciences sector, particularly those focused on thyroid hormone analogs, contrast agents, and targeted molecular probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thyroid hormone analogs and other iodinated bioactive molecules.
• Research & Development: Used as a specialized building block in medicinal chemistry for structure-activity relationship (SAR) studies and novel drug discovery.
• Diagnostic Agent Synthesis: Serves as a starting material for developing contrast agents and radioligands used in medical imaging (e.g., X-ray, SPECT).
• Biochemical Research: Employed in studies investigating protein-ligand interactions and enzyme inhibition where iodinated aromatic structures are required.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Alanine, 3-[4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl]-, Monosodium Salt (8Ci)
CAS No.	4406-42-2
Molecular Formula	C15H11I3NO4Na
Molecular Weight	688.96 g/mol
Synonyms	Monosodium 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]alanine; L-3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]alanine Monosodium Salt; 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]alanine Sodium Salt; Sodium 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]alaninate; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic Acid Sodium Salt; Alanine derivative CAS 4406-42-2; Iodinated Alanine Derivative
EINECS	Contact for details

Quality Control

Our Alanine, 3-[4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl]-, Monosodium Salt (8Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.