Description

3β-Hydroxypregnan-20-One is a high-purity steroid intermediate, also known as pregnanolone, with significant relevance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the production of neurosteroids and other specialized therapeutic agents, where precise molecular structure is paramount. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of neurological and hormonal treatments, requiring materials of exacting purity and reliable supply.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of neuroactive steroids like allopregnanolone.
• Neurosteroid Research: Used in biochemical studies to investigate GABA-A receptor modulation and related neurological pathways.
• Hormone Analog Development: Serves as a starting material for creating novel progesterone and corticosteroid analogs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC or GC-MS methods.
• Biochemical Reagent: Utilized in enzymatic studies and metabolic pathway research.

Basic Information

Product Name	3β-Hydroxypregnan-20-One
CAS No.	4406-37-5
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Pregnanolone; 3β-Hydroxy-5β-pregnan-20-one; 5β-Pregnan-3β-ol-20-one; Allopregnanolone (isomer); 3β,5β-Tetrahydroprogesterone; 5β-DHP; 3β-Hydroxy-5β-pregnane-20-one; 5β-Pregnane-3β,20α-diol (related)
EINECS	Contact for details

Quality Control

Our 3β-Hydroxypregnan-20-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines, and specifications can be aligned with client requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.