Description

n-(2-Hydroxyethyl)Adenosine is a chemically modified nucleoside derivative of adenosine, featuring a 2-hydroxyethyl group substitution. This modification is crucial for enhancing its solubility and altering its biological activity profile, making it a valuable intermediate for advanced research and synthesis. It is primarily utilized by pharmaceutical R&D teams, biochemical researchers, and fine chemical manufacturers developing novel therapeutic agents and nucleotide-based probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine kinases and deaminases.
• Probe Development: Serves as a precursor for fluorescently labeled or affinity-tagged nucleotides used in molecular biology and diagnostic assays.
• Life Science Reagents: Component in high-purity reagent kits for cell signaling pathway analysis and metabolic research.
• Fine Chemical Synthesis: Intermediate for creating specialized nucleotides with tailored properties for material science applications.

Basic Information

Product Name	n-(2-Hydroxyethyl)Adenosine
CAS No.	4338-48-1
Molecular Formula	C12H17N5O5
Molecular Weight	311.30 g/mol
Synonyms	2'-O-(2-Hydroxyethyl)adenosine; N6-(2-Hydroxyethyl)adenosine; Adenosine, N-(2-hydroxyethyl)-; HE-Ado; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[(2-hydroxyethyl)amino]purine
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxyethyl)Adenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture content. We provide Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.