Description

21-Hydroxy-4-Pregnene-3,20-Dione 21-Glucoside is a specific steroidal glucoside derivative, serving as a key intermediate in advanced pharmaceutical synthesis and biochemical research. Its value lies in its defined molecular structure, which is critical for the development and quality control of steroid-based active pharmaceutical ingredients (APIs). This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors requiring high-purity steroid precursors.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthetic pathways for corticosteroid and other steroidal APIs.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway investigations.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and assay development in pharmaceutical analysis.
• Process Development: Employed in the optimization and scale-up of steroid manufacturing processes within fine chemical production.
• Academic Research: Utilized in university and institutional labs for studies in organic chemistry, medicinal chemistry, and endocrinology.

Basic Information

Product Name	21-Hydroxy-4-Pregnene-3,20-Dione 21-Glucoside
CAS No.	4319-56-6
Molecular Formula	C27H40O9
Molecular Weight	508.60 g/mol
Synonyms	Cortisol 21-Glucoside; Hydrocortisone 21-Glucoside; 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-β-D-glucopyranoside; 21-Glucosylcortisol; Reichstein's Substance E 21-Glucoside; Cortisol 21-β-D-Glucoside; 21-O-β-D-Glucopyranosylcortisol
EINECS	Contact for details

Quality Control

Our 21-Hydroxy-4-Pregnene-3,20-Dione 21-Glucoside is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.