Description

4-Aminopyrazolopyrimidine-2'-Deoxyribofuranoside is a high-purity nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. Its value lies in its role as a versatile intermediate for the synthesis of modified oligonucleotides and potential therapeutic agents, particularly in antiviral and anticancer drug discovery. This compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA strands for antisense therapy, siRNA, and diagnostic probes.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and polymerase function.
• Medicinal Chemistry: A precursor for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Employed as a certified reference material (CRM) for quality control and analytical method development in QC laboratories.

Basic Information

Product Name	4-Aminopyrazolopyrimidine-2'-Deoxyribofuranoside
CAS No.	4302-99-2
Molecular Formula	C11H14N6O4
Molecular Weight	294.27 g/mol
Synonyms	4-Amino-1H-pyrazolo[3,4-d]pyrimidine-1-β-D-2'-deoxyribofuranoside; 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine; 4-APP; 4-Amino-pyrazolopyrimidine deoxyriboside; 4-Amino-1H-pyrazolo[3,4-d]pyrimidine-1-(2-deoxy-β-D-erythro-pentofuranoside); 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Aminopyrazolopyrimidine-2'-Deoxyribofuranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.