Description

16β-Acetoxy-14-Hydroxy-3-Oxo-5β,14β-Bufa-20,22-Dienolide CAS NO 4266-46-0 is a high-purity, specialized bufadienolide derivative. This compound is a critical advanced intermediate in the synthesis of complex bioactive molecules, valued for its specific stereochemistry and functional groups. It is primarily utilized by pharmaceutical research and development organizations, as well as by fine chemical manufacturers, for the development of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel cardioactive steroids and other therapeutic agents.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) of bufadienolide compounds.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, structurally modified derivatives for specialized applications.
• Academic Research: Utilized in university and institutional labs for chemical and biological research projects involving natural product derivatives.

Basic Information

Product Name	16β-Acetoxy-14-Hydroxy-3-Oxo-5β,14β-Bufa-20,22-Dienolide
CAS No.	4266-46-0
Molecular Formula	C₂₆H₃₄O₆
Molecular Weight	442.55 g/mol
Synonyms	16β-Acetoxy-14-hydroxy-3-oxo-5β,14β-bufa-20,22-dienolide; 14-Hydroxy-16β-acetoxy-3-oxo-5β,14β-bufa-20,22-dienolide; 3-Oxo-16β-acetoxy-14-hydroxy-5β,14β-bufa-20,22-dienolide; Bufadienolide derivative; 5β,14β-Bufadienolide-3-one, 16β-acetoxy-14-hydroxy-; (3β,5β,14β,16β)-14,16-Dihydroxy-3-oxobufa-20,22-dienolide 16-acetate
EINECS	Contact for details

Quality Control

Our 16β-Acetoxy-14-Hydroxy-3-Oxo-5β,14β-Bufa-20,22-Dienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.