Description

3-Phenylmethoxypropanoic Acid Chloride is a versatile acid chloride derivative used as a key building block in organic synthesis. This compound is critical for introducing the 3-phenylmethoxypropionyl moiety into target molecules, enabling the creation of complex chemical architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial reagent for the synthesis of active pharmaceutical ingredients (APIs), particularly in amide and ester bond formation.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific acyl group incorporation.
• Polymer Chemistry: Serves as a monomer or modifying agent for specialty polymers, including polyamides and polyesters with tailored properties.
• Peptide Mimetics & Linker Chemistry: Facilitates the construction of peptide analogs and the attachment of functional groups in bioconjugation and prodrug development.
• Liquid Crystal & OLED Material Precursor: Employed in the synthesis of advanced organic electronic materials and liquid crystal compounds.
• Fine Chemical & Flavor/Fragrance Intermediate: Used to synthesize complex esters and other derivatives for high-value chemical products.

Basic Information

Product Name	3-Phenylmethoxypropanoic Acid Chloride
CAS No.	4244-66-0
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	3-(Benzyloxy)propionyl chloride; Benzyloxypropionyl chloride; 3-(Phenylmethoxy)propanoyl chloride; β-(Benzyloxy)propionyl chloride; NSC 403697; 3-Benzyloxypropanoic acid chloride; Propanoic acid, 3-(phenylmethoxy)-, chloride
EINECS	224-215-3

Quality Control

Our 3-Phenylmethoxypropanoic Acid Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ISO 9001 standards for reliable integration into your synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed and handled under dry conditions to prevent hydrolysis. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.