Description

N,n-Dimethylguanosine 5''-Monophosphate is a chemically modified nucleotide monophosphate derivative of guanosine. This compound is valued for its role as a biochemical research tool and a potential precursor in the synthesis of specialized nucleotides and oligonucleotides. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, enzymology studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphatases, and other nucleotide-processing enzymes.
• Nucleic Acid Chemistry: Serves as a building block or modified precursor for the solid-phase synthesis of oligonucleotides with specific structural or functional properties.
• Pharmaceutical R&D: Investigated for its potential in the development of nucleotide-based prodrugs, antiviral agents, or tools for studying cellular signaling pathways.
• Diagnostic Reagent Development: Can be incorporated into probes or assay components for detecting specific enzymatic activities or biomolecular interactions.
• Enzyme Mechanism Studies: Employed to explore the substrate specificity and catalytic mechanisms of purine-nucleotide utilizing enzymes.

Basic Information

Product Name	N,n-Dimethylguanosine 5''-Monophosphate
CAS No.	4214-21-5
Molecular Formula	C₁₂H₁₈N₆O₈P
Molecular Weight	396.28 g/mol
Synonyms	N,N-Dimethylguanosine 5'-monophosphate; 5'-GMP-N,N-dimethyl; 2-(Dimethylamino)-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-1H-purin-6-one; N,N-Dimethyl-5'-GMP; Dimethyl-GMP; Guanosine, N,N-dimethyl-, 5'-(dihydrogen phosphate); 5'-O-Phosphono-N,N-dimethylguanosine
EINECS	Contact for details

Quality Control

Our N,n-Dimethylguanosine 5''-Monophosphate is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation by spectroscopic methods. Certificates of Analysis (COA) detailing all relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.