Description

[[5-(2,4-Dioxopyrimidin-1-Yl)-3-Hydroxy-Oxolan-2-Yl]Methoxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid is a sophisticated nucleoside phosphonate derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical high-purity building block for the synthesis of novel antiviral and anticancer nucleotide analogs. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleotide-based prodrugs and antiviral agents targeting viral polymerases.
• Antiviral Drug Research: Building block for developing novel nucleoside phosphonate analogs with potential activity against a range of DNA and RNA viruses.
• Oncology Research: Used in the design and synthesis of experimental chemotherapeutic agents that interfere with DNA synthesis and replication.
• Biochemical Tool Compound: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and polymerase function.
• Fine Chemical Synthesis: Intermediate for creating modified nucleosides with tailored biological properties for specialized applications.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for complex nucleotide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	[[5-(2,4-Dioxopyrimidin-1-Yl)-3-Hydroxy-Oxolan-2-Yl]Methoxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid
CAS No.	4208-67-7
Molecular Formula	C10H14N2O12P2
Molecular Weight	416.17 g/mol
Synonyms	Uridine 5'-(Dihydrogen Diphosphate); P1-(5'-Uridyl) P2-(Dihydrogen) Diphosphate; Uridine 5'-Diphosphoric Acid; UDP; Uridine Diphosphate; Uridine Pyrophosphate; 5'-UDP; Uridine 5'-Pyrophosphate
EINECS	224-124-8

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and cGMP manufacturing needs with documentation suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.