Description

Dimethyl Acetylmethylphosphonate is a versatile organophosphorus compound with a reactive β-ketophosphonate structure. This chemical serves as a critical building block in organic synthesis, enabling the formation of complex molecules through its unique reactivity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing carbon-carbon and carbon-heteroatom bonds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phosphorus or complex ketone functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel phosphonate-based ligands for metal catalysis.
• Material Science: Employed in the research and development of flame retardants, plasticizers, and other functional polymer additives.
• Organic Synthesis Reagent: A valuable reagent for Horner-Wadsworth-Emmons (HWE) olefination reactions to synthesize alkenes, as well as for Michael additions and other nucleophilic reactions.
• Chemical Research: Fundamental building block in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Item	Details
Product Name	Dimethyl Acetylmethylphosphonate
CAS No.	4202-14-6
Molecular Formula	C5H11O4P
Molecular Weight	166.11 g/mol
Synonyms	Acetylmethylphosphonic Acid Dimethyl Ester; Dimethyl (2-Oxopropyl)phosphonate; 2-Oxopropylphosphonic Acid Dimethyl Ester; Dimethyl 2-Oxopropylphosphonate; (2-Oxopropyl)phosphonic Acid Dimethyl Ester; DMAMP; Acetyl Methyl Phosphonate Dimethyl Ester
EINECS	224-119-9

Quality Control

Our Dimethyl Acetylmethylphosphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.