Description

3-Oxo-7α-Hydroxy-5β-Cholanoic Acid is a high-purity bile acid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its value lies in its defined stereochemistry and functional groups, which are essential for producing specific therapeutic agents and reference standards. This compound is primarily needed by manufacturers and R&D teams in the pharmaceutical, biotechnology, and fine chemical sectors for developing steroid-based drugs and metabolic research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of steroidal drugs and therapeutic bile acids.
• Biochemical Research: Used as a reference standard or substrate in studies of liver metabolism, cholesterol homeostasis, and bile acid pathways.
• Fine Chemical Synthesis: Serves as a chiral starting material for the production of complex organic molecules with specific biological activity.
• Diagnostic Reagents: Potential use in the formulation of calibration standards for clinical diagnostic assays related to liver function.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry within university and corporate laboratories.

Basic Information

Product Name	3-Oxo-7α-Hydroxy-5β-Cholanoic Acid
CAS No.	4185-00-6
Molecular Formula	C₂₄H₃₈O₅
Molecular Weight	406.56 g/mol
Synonyms	7α-Hydroxy-3-oxo-5β-cholan-24-oic Acid; 3-Keto-7α-hydroxy-5β-cholanoic Acid; 7α-Hydroxy-3-oxocholanoic Acid; 3-Oxochenodeoxycholic Acid; 3-Oxo-7α-hydroxy-5β-cholanic Acid; 7α-Hydroxy-3-oxo-5β-cholanic Acid; 3-Ketochenodeoxycholic Acid; 4185-00-6
EINECS	224-058-5

Quality Control

Our 3-Oxo-7α-Hydroxy-5β-Cholanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates and research chemicals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.