Description

Di(p-Tolyl)Phosphinoyl Chloride is a versatile organophosphorus reagent, specifically a phosphinic chloride derivative. This compound is a critical building block in organic synthesis, valued for its role in forming P-C and P-O bonds to create complex phosphine oxide and phosphonate ligands. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for catalyst development and the synthesis of advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel phosphine oxide-based drug candidates and active pharmaceutical ingredients (APIs).
• Ligand Synthesis: Used to manufacture sophisticated phosphine oxide and phosphinite ligands for homogeneous catalysis, including cross-coupling reactions.
• Agrochemical Production: Building block for creating new generations of herbicides, fungicides, and plant growth regulators with phosphorous backbones.
• Polymer Modification: Employed as a functionalization agent to introduce phosphinoyl groups into polymers, altering flame retardancy or metal-binding properties.
• Material Science Research: Used in developing advanced materials such as metal-organic frameworks (MOFs) and organic electronics.
• Chemical Synthesis Reagent: Acts as a phosphorylating agent in organic laboratories for the preparation of esters and amides of phosphinic acids.

Basic Information

Product Name	Di(p-Tolyl)Phosphinoyl Chloride
CAS No.	4129-40-2
Molecular Formula	C14H14ClOP
Molecular Weight	264.68 g/mol
Synonyms	Bis(4-methylphenyl)phosphinic chloride; Di(4-tolyl)phosphinic chloride; p-Tolylphosphonic dichloride (related); Phosphinic chloride, bis(4-methylphenyl)-; Di-p-tolylphosphinic chloride; 4-Methylphenylphosphonic dichloride derivative; Chlorodi-p-tolylphosphine oxide
EINECS	Contact for details

Quality Control

Our Di(p-Tolyl)Phosphinoyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.