Description

Dideoxyadenosine is a synthetic nucleoside analog that serves as a critical building block and research reagent. Its primary value lies in its role as a chain terminator in molecular biology and its use in the synthesis of modified oligonucleotides. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing antiviral agents, diagnostic probes, and novel nucleic acid-based therapeutics. Dideoxyadenosine CAS NO 4097-22-7 is a high-purity specialty chemical for advanced life science applications.

Application

• Molecular Biology Research: Used as a chain-terminating substrate in Sanger DNA sequencing and related enzymatic studies.
• Antiviral Drug Development: Serves as a precursor or analog in the research and synthesis of nucleoside reverse transcriptase inhibitors (NRTIs).
• Oligonucleotide Synthesis: A key raw material for the chemical synthesis of modified DNA and RNA strands for diagnostic and therapeutic applications.
• Biochemical Assays: Employed as a standard or inhibitor in enzymatic assays studying polymerase and kinase activity.
• Academic & Pharmaceutical R&D: Fundamental reagent for investigating nucleic acid metabolism, enzyme mechanisms, and drug discovery pathways.
• Diagnostic Probe Manufacturing: Used in the production of labeled nucleotides for techniques like FISH (Fluorescence In Situ Hybridization).

Basic Information

Product Name	Dideoxyadenosine
CAS No.	4097-22-7
Molecular Formula	C10H13N5O2
Molecular Weight	235.25 g/mol
Synonyms	2',3'-Dideoxyadenosine; ddA; DDA; 9-[(2R,5S)-5-(Hydroxymethyl)oxolan-2-yl]purin-6-amine; Cordycepin analog; 2',3'-ddAdo; NSC 10764; 2',3'-Dideoxy-D-adenosine
EINECS	223-862-8

Quality Control

Our Dideoxyadenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is characterized and released according to comprehensive analytical procedures, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support cGMP and ISO standards for research and pharmaceutical-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.