Description

3β-Acetoxy-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide CAS NO 4064-09-9 is a high-purity bufadienolide derivative, a specialized class of steroid-like compounds with significant biological activity. This compound is valued for its role as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of cardiology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthetic pathways for novel bufadienolide-based drug candidates.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the structure-activity relationships (SAR) of cardiac glycosides and related compounds.
• API Development: A crucial starting material or intermediate in the development of Active Pharmaceutical Ingredients (APIs) targeting specific ion channels and cellular pumps.
• Academic Research: Utilized in university and institutional labs for fundamental studies on natural product chemistry, biosynthesis, and medicinal chemistry.

Basic Information

Product Name	3β-Acetoxy-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide
CAS No.	4064-09-9
Molecular Formula	C₂₆H₃₄O₇
Molecular Weight	458.55 g/mol
Synonyms	19-Oxocinobufagin 3-acetate; 3β-Acetoxy-5,14-dihydroxy-19-oxo-5β-bufa-20,22-dienolide; 3β-Acetoxy-14-hydroxy-19-oxo-5β-bufa-20,22-dienolide; Cinobufagin 3-acetate; 19-Oxocinobufagin-3-acetate; Bufadienolide derivative 4064-09-9; 5,14-Dihydroxy-19-oxo-3β-(acetyloxy)-5β-bufa-20,22-dienolide
EINECS	Contact for details

Quality Control

Every batch of 3β-Acetoxy-5,14-Dihydroxy-19-Oxo-5β-Bufa-20,22-Dienolide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.