Description

3β,11β,17,21-Tetrahydroxy-5β-Pregnan-20-One 21-Acetate is a high-purity steroid derivative and a key intermediate in the synthesis of more complex pharmaceutical compounds. Its precise stereochemistry and functional groups make it a valuable building block for research and development in the pharmaceutical industry. This compound is primarily utilized by manufacturers and research institutions focused on developing corticosteroids and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent corticosteroid drugs, including hydrocortisone and its derivatives.
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and steroid hormone research.
• Process Development: Serves as a key intermediate for optimizing and scaling up production processes for steroid-based active pharmaceutical ingredients (APIs).
• Analytical Standard: Employed in analytical laboratories for method development, calibration, and quality control testing of related steroid products.

Basic Information

Product Name	3β,11β,17,21-Tetrahydroxy-5β-Pregnan-20-One 21-Acetate
CAS No.	4047-40-9
Molecular Formula	C23H36O6
Molecular Weight	408.53 g/mol
Synonyms	21-Acetoxy-3β,11β,17,21-tetrahydroxy-5β-pregnan-20-one; 3β,11β,17,21-Tetrahydroxypregnan-20-one 21-acetate; 5β-Pregnane-3β,11β,17,21-tetrol-20-one 21-acetate; 11β,17,21-Trihydroxy-3β-hydroxy-5β-pregnan-20-one 21-acetate; Tetrahydrocortisone 21-acetate; THE 21-acetate; 3β,11β,17,21-Tetrahydroxy-5β-pregnan-20-one 21-acetate; 5β-Tetrahydrocortisone 21-acetate
EINECS	Contact for details

Quality Control

Our 3β,11β,17,21-Tetrahydroxy-5β-Pregnan-20-One 21-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.