Description

1,4-Phenylene Diisothiocyanate is a high-purity organic compound widely used as a critical building block in advanced chemical synthesis. Its value lies in its dual isothiocyanate functional groups, which enable efficient cross-linking and derivatization reactions under controlled conditions. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries, particularly for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of potential drug candidates, especially for creating urea and thiourea derivatives with biological activity.
• Polymer Chemistry: Serves as a cross-linking agent and monomer for producing specialized polyurethanes, polyureas, and other high-performance polymers with enhanced thermal and mechanical properties.
• Bioconjugation & Protein Labeling: Used to modify peptides, proteins, and antibodies by reacting with amine groups, facilitating the study of biomolecular interactions.
• Agrochemical Synthesis: Intermediate in the production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of advanced organic frameworks, coatings, and adhesives requiring specific reactivity profiles.
• Analytical Chemistry: Can be used as a derivatization agent in chromatography for the detection and quantification of amines and amino acids.

Basic Information

Product Name	1,4-Phenylene Diisothiocyanate
CAS No.	4044-65-9
Molecular Formula	C8H4N2S2
Molecular Weight	192.26 g/mol
Synonyms	p-Phenylene Diisothiocyanate; 1,4-Diisothiocyanatobenzene; PDI; Phenylenediisothiocyanate; Benzene-1,4-diyl diisothiocyanate; NSC 403016; 4-Isothiocyanatophenyl isothiocyanate; p-Xylylene diisothiocyanate (related)
EINECS	223-757-4

Quality Control

Our 1,4-Phenylene Diisothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation by FT-IR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	130 - 134 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.