Description

3-o-Acetylbufotalin is a chemically modified bufadienolide derivative, a class of compounds known for their potent biological activity. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of cardiac glycosides and their therapeutic potential. It serves as an essential analytical standard and research chemical for laboratories in the pharmaceutical, biotechnology, and academic sectors focused on oncology, cardiology, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of bufadienolide compounds in drug discovery and quality control.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the mechanism of action, cytotoxicity, and pharmacological effects of cardiac glycosides.
• Natural Product Isolation & Analysis: Serves as a key analytical marker for the identification and standardization of toad venom extracts and related traditional medicines.
• Academic Research: A vital tool for universities and research institutes studying steroid biochemistry, cell signaling pathways, and structure-activity relationships (SAR).
• Preclinical Development: Utilized in the early-stage development of novel therapeutic agents targeting specific enzymes or cellular receptors.

Basic Information

Product Name	3-o-Acetylbufotalin
CAS No.	4029-69-0
Molecular Formula	C26H34O6
Molecular Weight	442.55 g/mol
Synonyms	3-O-Acetylbufotalin; Bufotalin 3-acetate; 3β-Acetoxy-14,15-epoxy-5β-bufa-20,22-dienolide; 14β,15β-Epoxy-3β-hydroxy-5β-bufa-20,22-dienolide 3-acetate; 3-Acetylbufotalin; NSC 89239; Bufotalin acetate
EINECS	Contact for details

Quality Control

Our 3-o-Acetylbufotalin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for research and reference standards. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.