Description

3-Oxo-14-Hydroxy-5β-Bufa-20,22-Dienolide is a high-purity steroidal compound belonging to the bufadienolide class, known for its specific structural configuration and biological activity. This compound is critical for advanced pharmaceutical research and development, particularly in the study of cardiac glycosides and their mechanisms. It serves as a key intermediate or reference standard for researchers and manufacturers in the life sciences sector requiring precise molecular tools.

Application

• Pharmaceutical Research & Development: Acts as a crucial intermediate in the synthesis of novel therapeutic agents, particularly those targeting cardiac function.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Biochemical Studies: Employed in pharmacological and toxicological research to investigate the structure-activity relationships (SAR) of bufadienolides.
• Academic Research: Serves as a reagent in university and institutional labs for studying natural product chemistry and steroid biosynthesis pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and pilot-scale production.

Basic Information

Product Name	3-Oxo-14-Hydroxy-5β-Bufa-20,22-Dienolide
CAS No.	4029-65-6
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	14-Hydroxy-3-oxo-5β-bufa-20,22-dienolide; 3-Oxo-14-hydroxybufa-20,22-dienolide; 5β-Bufa-20,22-dienolide-3,14-dione; Bufadienolide derivative; Scillarenin analog; 4029-65-6; 14-Hydroxy-3-oxocard-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3-Oxo-14-Hydroxy-5β-Bufa-20,22-Dienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.