Description

Desacetylcinobufagin is a bioactive bufadienolide compound derived from natural sources. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of cardiac glycosides and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories engaged in drug discovery, pharmacological studies, and quality control of related herbal products.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the identification, assay, and impurity profiling of related pharmaceutical compounds and herbal extracts.
• Drug Discovery & Development: Used as a key intermediate or active pharmaceutical ingredient (API) in preclinical research for investigating new therapeutic agents, especially in oncology and cardiology.
• Biochemical Research: Employed in in-vitro and in-vivo studies to elucidate mechanisms of action, pharmacokinetics, and structure-activity relationships (SAR) of bufadienolides.
• Analytical Chemistry: Essential for method development and validation in analytical techniques such as HPLC, LC-MS, and NMR for quality control in manufacturing.
• Academic Research: A vital tool for universities and research institutes studying natural product chemistry, toxicology, and biosynthetic pathways.

Basic Information

Product Name	Desacetylcinobufagin
CAS No.	4026-95-3
Molecular Formula	C24H32O5
Molecular Weight	400.51 g/mol
Synonyms	3β,14-Dihydroxy-5β-bufa-20,22-dienolide; 3β-Hydroxy-14,15β-epoxy-5β-bufa-20,22-dienolide; Desacetylcinobufagin; Cinobufagin-3-ol; Bufogenin B; NSC 83265; Cinobufagin aglycone
EINECS	Contact for details

Quality Control

Our Desacetylcinobufagin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.