Description

Uridine 3',5'-Cyclic Monophosphate is a biologically significant cyclic nucleotide derivative of uridine. This compound serves as a crucial second messenger and research tool in cellular signaling pathways, particularly those involving cyclic nucleotide-gated ion channels and protein kinases. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for biochemical research, diagnostic assay development, and as a reference standard.

Application

• Biochemical Research: Used as a key reagent in studying cyclic nucleotide-mediated signal transduction, enzyme kinetics (e.g., phosphodiesterases), and receptor-ligand interactions.
• Pharmaceutical Development: Serves as a critical intermediate or reference standard in the development of nucleotide-based therapeutics and metabolic pathway modulators.
• Diagnostic Assays: Employed in the formulation of enzyme-linked immunosorbent assays (ELISAs) and other diagnostic kits for research and clinical testing.
• Cell Culture & Neuroscience: Applied in cell signaling studies, particularly in neurological research to investigate the role of cyclic nucleotides in neuronal function and plasticity.
• Enzyme Substrate: Acts as a specific substrate for phosphodiesterase enzymes in activity assays and inhibitor screening programs.

Basic Information

Product Name	Uridine 3',5'-Cyclic Monophosphate
CAS No.	4004-57-3
Molecular Formula	C10H12N2O9P
Molecular Weight	344.18 g/mol
Synonyms	Uridine 3',5'-cyclic monophosphate; Uridine 3',5'-cyclic phosphate; 3',5'-cUMP; Cyclic UMP; cUMP; Uridine cyclic 3',5'-(hydrogen phosphate); Uridine 3',5'-monophosphate, cyclic; 3',5'-Cyclic UMP
EINECS	223-663-1

Quality Control

Our Uridine 3',5'-Cyclic Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.