Description

Proxymetacaine CAS NO 499-67-2 is a potent local anesthetic agent belonging to the ester class, specifically designed for rapid onset and short duration of action. Its primary value lies in providing effective surface anesthesia with minimal irritation, making it a critical component in sensitive medical procedures. This compound is essential for manufacturers in the pharmaceutical and ophthalmic sectors, where it is formulated into diagnostic and therapeutic solutions.

Application

• Ophthalmic Anesthesia: Primary use as a topical anesthetic for eye examinations (tonometry), foreign body removal, and minor surgical procedures.
• Diagnostic Agent: Formulated in eye drops to facilitate painless diagnostic tests and measurements of intraocular pressure.
• Pharmaceutical Intermediates: Serves as a key chemical building block in the synthesis of more complex anesthetic agents.
• Veterinary Medicine: Used in topical formulations for ophthalmic procedures in animals.
• Research & Development: Utilized in pharmacological studies and the development of new local anesthetic formulations.

Basic Information

Product Name	Proxymetacaine
CAS No.	499-67-2
Molecular Formula	C16H26N2O3
Molecular Weight	294.39 g/mol
Synonyms	Proparacaine; Ophthalme; Alcaine; Proxymetacaine Hydrochloride; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate; Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester; Proparacaine HCl
EINECS	207-879-7

Quality Control

Our Proxymetacaine is manufactured under strict quality management systems to ensure it meets the stringent requirements of pharmaceutical applications. We provide comprehensive quality documentation, including Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. The product can be supplied to meet various pharmacopeial standards, including USP and EP monographs, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.